Compound Q&A
How is Tert-butyl 4-amino-1H-indazole-1-carboxylate (CAS: 8016-13-5) typically synthesized?
Answer
Tert-butyl 4-amino-1H-indazole-1-carboxylate can be synthesized via the coupling of tert-butyl 4-bromomethyl-1H-indazole-1-carboxylate with an amine. The reaction typically requires a base such as potassium carbonate and is performed in an aprotic solvent like N,N-dimethylformamide (DMF) under an inert atmosphere. The yield is generally around 70-80%, with good selectivity towards the desired product.
About
CAS No
8016-13-5
English Name
Tert-butyl 4-amino-1H-indazole-1-carboxylate
Molecular Formula
C12H15N3O2
Molecular Weight
233.27 g/mol
SMILES
O(C(N1C2C=CC=C(C=2C=N1)N)=O)C(C)(C)C
InChIKey
LBOHJOLQKZNKFB-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55
