Compound Q&A
How is 5-Bromo-8-fluoroquinoline (CAS: 1133115-78-2) typically synthesized?
Answer
5-Bromo-8-fluoroquinoline is typically synthesized by bromination of 8-fluoroquinoline. The reaction is catalyzed by N-chlorosuccinimide (NCS) and usually yields a high purity product. Other methods include the use of bromine in the presence of a phase-transfer catalyst. The reaction is selective and provides good yield.
About
CAS No
1133115-78-2
English Name
5-Bromo-8-fluoroquinoline
Molecular Formula
C9H5BrFN
Molecular Weight
226.05 g/mol
SMILES
Fc1ccc(Br)c2cccnc12
InChIKey
KXPOUFUCFZQOQE-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18
