Compound Q&A
How is 7-Deaza-2'-dG (CAS: 86392-75-8) typically synthesized?
Answer
7-Deaza-2'-dG can be synthesized via a multistep process where the 7-deazapyrimidine ring is built from precursors such as 6-azauridine. Common methods include nucleophilic substitution and condensation reactions. The key steps involve the installation of the 2'-hydroxyl group and the 7-deazapyrimidine core. Catalysts like organic acids or bases may be used, and the overall yield typically ranges from 60% to 80%. High selectivity for the desired product is achieved through careful control of reaction conditions.
About
CAS No
86392-75-8
English Name
7-Deaza-2'-dG
Molecular Formula
C11H14N4O4
Molecular Weight
266.26 g/mol
SMILES
O=C1C2=C(N([C@@H]3C[C@@H]([C@@H](CO)O3)O)C=C2)NC(N)=N1
InChIKey
PFCLMNDDPTZJHQ-RNJXMRFFSA-N
Last Updated: 2025-10-13 11:18
