Compound Q&A

How is 1,3-Dimethyl-1H-pyrazol-5-amine (CAS: 3524-32-1) typically synthesized?

Answer

1,3-Dimethyl-1H-pyrazol-5-amine
1,3-Dimethyl-1H-pyrazol-5-amine (CAS: 3524-32-1) can be synthesized via the Biginelli reaction, where 5-aminomethyl-3-methylpyrazole reacts with methyl acetoacetate in the presence of an acid catalyst such as sulfuric acid. The reaction is carried out at temperatures between 80-100°C, and the yield can be up to 90% depending on the purity of the starting materials.

About

CAS No 3524-32-1
English Name 1,3-Dimethyl-1H-pyrazol-5-amine
Molecular Formula C5H9N3
Molecular Weight 111.14800000000002 g/mol
SMILES CC1=NN(C(=C1)N)C
InChIKey ZFDGMMZLXSFNFU-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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