Compound Q&A

How is 6-(Trifluoromethyl)-4(1H)-pyrimidinone (CAS: 1546-78-7) typically synthesized?

Answer

6-(Trifluoromethyl)-4(1H)-pyrimidinone
6-(Trifluoromethyl)-4(1H)-pyrimidinone (CAS: 1546-78-7) can be synthesized via several routes, commonly involving the reaction of 4-chloropyrimidin-2-one with trifluoroacetyl chloride. The process typically requires the use of a catalyst and proceeds with good selectivity and yield. Detailed synthesis methods and conditions are available in the literature.

About

CAS No 1546-78-7
English Name 6-(Trifluoromethyl)-4(1H)-pyrimidinone
Molecular Formula C5H3F3N2O
Molecular Weight 164.09 g/mol
SMILES C1=C(N=CNC1=O)C(F)(F)F
InChIKey LVOYSBZJJWPUBD-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10

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