Compound Q&A

How is Methyl 2-bromo-1,3-thiazole-4-carboxylate (CAS: 170235-26-4) typically synthesized?

Answer

Methyl 2-bromo-1,3-thiazole-4-carboxylate
Methyl 2-bromo-1,3-thiazole-4-carboxylate (CAS: 170235-26-4) is typically synthesized by reacting 1,3-thiazole-4-carboxylic acid with bromine in the presence of a suitable solvent like acetic anhydride or acetic acid. The reaction is highly selective and provides good yield, with the product being isolated via recrystallization from appropriate solvents.

About

English Name Methyl 2-bromo-1,3-thiazole-4-carboxylate
Molecular Formula C5H4BrNO2S
Molecular Weight 222.06 g/mol
SMILES COC(=O)C1=CSC(=N1)Br
InChIKey YOWKNNKTQWCYNC-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10

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