Methyl 2-bromo-1,3-thiazole-4-carboxylate(CAS: 170235-26-4)

Methyl 2-bromo-1,3-thiazole-4-carboxylate (CAS: 170235-26-4) is a crystalline solid with a molecular weight of approximately 262.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dimethylformamide. This compound is moderately reactive, particularly towards nucleophilic substitution reactions, and can undergo hydrolysis under acidic conditions. It is used as a precursor in organic synthesis and pharmaceuticals.

Methyl 2-bromo-1,3-thiazole-4-carboxylate (CAS: 170235-26-4) is typically synthesized by reacting 1,3-thiazole-4-carboxylic acid with bromine in the presence of a suitable solvent like acetic anhydride or acetic acid. The reaction is highly selective and provides good yield, with the product being isolated via recrystallization from appropriate solvents.

Methyl 2-bromo-1,3-thiazole-4-carboxylate (CAS: 170235-26-4) is used in the pharmaceutical industry as a precursor for the synthesis of various bioactive molecules, including antibiotics and antiviral agents. It is also utilized in the polymer industry for the modification of polymers, and in the sensor industry for developing chemical and biological sensors.

When handling Methyl 2-bromo-1,3-thiazole-4-carboxylate (CAS: 170235-26-4), it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, it should be cleaned up immediately using appropriate spill response materials. Always refer to the Safety Data Sheet (SDS) for detailed safety guidelines.