Compound Q&A

How is 4-Amino-5-(ethylsulfanyl)-2-methoxybenzoic acid (CAS: 71675-86-0) typically synthesized?

Answer

4-Amino-5-(ethylsulfanyl)-2-methoxybenzoic acid
4-Amino-5-(ethylsulfanyl)-2-methoxybenzoic acid is typically synthesized via a multi-step procedure involving the protection of the hydroxyl group of 2-methoxybenzoic acid followed by sulfenylation with ethanethiol, followed by deprotection and amidation. Key reagents include 4-nitrotoluene, ethanethiol, and sodium hydroxide. The yield is around 70-75%, and the reaction is conducted under basic conditions.

About

CAS No 71675-86-0
English Name 4-Amino-5-(ethylsulfanyl)-2-methoxybenzoic acid
Molecular Formula C10H13NO3S
Molecular Weight 227.29 g/mol
SMILES CCSC1=C(C=C(C(=C1)C(=O)O)OC)N
InChIKey BVCKAIGDWABZIE-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10

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