Compound Q&A
How is Ethyl 2-amino-4-methyl-3-thiophenecarboxylate (CAS: 43088-42-2) typically synthesized?
Answer
Ethyl 2-amino-4-methyl-3-thiophenecarboxylate (CAS: 43088-42-2) is commonly synthesized through an amidation reaction of 4-methyl-3-thiophenecarboxylic acid and ethyl amine. The reaction proceeds efficiently at room temperature using anhydrous conditions. Catalysts such as triethylamine or dicyclohexylcarbodiimide (DCC) are often employed to increase yield and selectivity.
About
CAS No
43088-42-2
English Name
Ethyl 2-amino-4-methyl-3-thiophenecarboxylate
Molecular Formula
C8H11NO2S
Molecular Weight
185.25 g/mol
SMILES
CCOC(=O)C1=C(SC=C1C)N
InChIKey
ILYCZKOBLRJJSW-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10
