Compound Q&A

How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(2-methyl-2-propanyl)-L-tyrosine (CAS: 133373-24-7) typically synthesized?

Answer

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(2-methyl-2-propanyl)-L-tyrosine
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(2-methyl-2-propanyl)-L-tyrosine (CAS: 133373-24-7) is synthesized through multi-step reactions involving protection, modification, and deprotection of L-tyrosine. Commonly, it involves the use of fluorenylmethoxycarbonyl (Fmoc) protection, followed by selective modifications. The final deprotection yields the desired compound with high yield and selectivity, often achieved with careful control of pH and temperature.

About

English Name N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(2-methyl-2-propanyl)-L-tyrosine
Molecular Formula C29H31NO5
Molecular Weight 473.57 g/mol
SMILES CC(C)(C)Oc1ccc(cc1)C[C@@H](C(=O)O)N(C)C(=O)OCC2c3ccccc3-c4c2cccc4
InChIKey WTLSDEYZKFJXFT-SANMLTNESA-N
Last Updated: 2025-10-10 21:10

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