How is Tetrahydro-2H-pyran-4-ylacetic acid (CAS: 85064-61-5) typically synthesized?

Tetrahydro-2H-pyran-4-ylacetic acid is typically synthesized via acid catalyzed ring opening of 4-hydroxytetrahydro-2H-pyran followed by acylation. The synthesis is performed using mild conditions to ensure good yield and selectivity. Common catalysts include sulfuric acid or hydrochloric acid, and the reaction can be conducted in water or an organic solvent such as methanol.