Tetrahydro-2H-pyran-4-ylacetic acid(CAS: 85064-61-5)

Tetrahydro-2H-pyran-4-ylacetic acid (CAS: 85064-61-5) is a colorless to white crystalline solid with a molecular weight of approximately 192.2 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. Reactivity is moderate, with a tendency to form esters and amides. The compound exhibits basic properties and can react with acids to form salts.

Tetrahydro-2H-pyran-4-ylacetic acid is typically synthesized via acid catalyzed ring opening of 4-hydroxytetrahydro-2H-pyran followed by acylation. The synthesis is performed using mild conditions to ensure good yield and selectivity. Common catalysts include sulfuric acid or hydrochloric acid, and the reaction can be conducted in water or an organic solvent such as methanol.

Tetrahydro-2H-pyran-4-ylacetic acid (CAS: 85064-61-5) is widely used in the pharmaceutical and polymer industries. It serves as a precursor in the synthesis of medicinals and in the production of polyurethane and other polymers. Additionally, it is used in the development of sensors and as a chelating agent in various applications.

When handling Tetrahydro-2H-pyran-4-ylacetic acid (CAS: 85064-61-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure to work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.