Compound Q&A

How is Methyl 3-(trimethylsilyl)-4-pentenoate (CAS: 185411-12-5) typically synthesized?

Answer

Methyl 3-(trimethylsilyl)-4-pentenoate
Methyl 3-(trimethylsilyl)-4-pentenoate is typically synthesized via the Wittig reaction, where 4-pentenoyl chloride reacts with trimethylsilyl triflate in the presence of a base like triethylamine. The reaction is conducted under an inert atmosphere to prevent side reactions. This method provides good yields and high selectivity, with the product being purified by distillation or column chromatography.

About

English Name Methyl 3-(trimethylsilyl)-4-pentenoate
Molecular Formula C9H18O2Si
Molecular Weight 186.33 g/mol
SMILES COC(=O)CC(C=C)[Si](C)(C)C
InChIKey DJXDHDYQDMVTPZ-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51

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