Compound Q&A
How is 5-[(3-Chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid (CAS: 1009820-21-6) typically synthesized?
Answer
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The compound can be synthesized via a multi-step process involving amide formation and condensation reactions. A typical method involves the coupling of 3-chloroaniline with 8-carboxybenzo[c][2,6]naphthyridine using a suitable coupling agent like HATU in the presence of a base such as DIPEA. The yield is around 75-80%, and the product can be purified by recrystallization from appropriate solvents.
About
CAS No
1009820-21-6
English Name
5-[(3-Chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid
Molecular Formula
C19H12ClN3O2
Molecular Weight
349.78 g/mol
SMILES
OC(=O)c1ccc2c(c1)nc(Nc3cccc(Cl)c3)c4ccncc42
InChIKey
MUOKSQABCJCOPU-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51
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