Compound Q&A
How is 1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one (CAS: 4424-80-0) typically synthesized?
Answer
1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one is typically synthesized via the condensation of 2-amino-1,3,4,5-tetrahydro-2H-1-benzazepine with acetyl chloride in the presence of a base like potassium carbonate. The reaction is carried out in an organic solvent such as acetone, and the product is isolated by filtration and recrystallization. The yield is generally around 70-80%.
About
CAS No
4424-80-0
English Name
1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one
Molecular Formula
C10H11NO
Molecular Weight
161.2 g/mol
SMILES
C1CC2=CC=CC=C2NC(=O)C1
InChIKey
HRVRAYIYXRVAPR-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51
