Compound Q&A
How is 1-Ethoxy-2,2-difluoroethanol (CAS: 148992-43-2) typically synthesized?
Answer
1-Ethoxy-2,2-difluoroethanol (CAS: 148992-43-2) can be synthesized through a dehydrofluorination reaction of ethyl 2,2-difluoroacetate with sodium ethoxide. The reaction involves a palladium catalyst and typically yields a product with >95% purity. The process is conducted under mild conditions to maintain the integrity of the functional groups.
About
CAS No
148992-43-2
English Name
1-Ethoxy-2,2-difluoroethanol
Molecular Formula
C4H8F2O2
Molecular Weight
126.1 g/mol
SMILES
CCOC(C(F)F)O
InChIKey
WEEOMNFWRCDRJI-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21
