Compound Q&A

How is 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone (CAS: 586-60-7) typically synthesized?

Answer

1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone
1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone (CAS: 586-60-7) is commonly synthesized via a multistep reaction involving the coupling of 4-butoxybenzaldehyde and 1-piperidinecarboxaldehyde. The reaction is typically catalyzed by a catalyst such as DMAP (4-Dimethylaminopyridine) or HOBt (1-Hydroxybenzotriazole). High selectivity and good yield are achieved, making this compound a valuable intermediate in various organic synthesis processes.

About

CAS No 586-60-7
English Name 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone
Molecular Formula C18H27NO2
Molecular Weight 289.42 g/mol
SMILES CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2
InChIKey BZEWSEKUUPWQDQ-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21

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