1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone(CAS: 586-60-7)

1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone (CAS: 586-60-7) is a colorless to white crystalline solid with a molecular weight of approximately 255.34 g/mol. It is slightly soluble in water but freely soluble in organic solvents like ethanol and chloroform. This compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It is also known for its low volatility and stability under normal conditions.

1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone (CAS: 586-60-7) is commonly synthesized via a multistep reaction involving the coupling of 4-butoxybenzaldehyde and 1-piperidinecarboxaldehyde. The reaction is typically catalyzed by a catalyst such as DMAP (4-Dimethylaminopyridine) or HOBt (1-Hydroxybenzotriazole). High selectivity and good yield are achieved, making this compound a valuable intermediate in various organic synthesis processes.

1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone (CAS: 586-60-7) is primarily used in pharmaceuticals and as a key intermediate in the synthesis of various organic compounds. It is also utilized in the development of polymer additives, sensors, and semiconductors, due to its unique chemical properties and reactivity.

When handling 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone (CAS: 586-60-7), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. This compound should be handled in a well-ventilated area or under a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly rinsed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety guidelines and emergency procedures.