Compound Q&A

How is 2-Bromo-4,5-difluorobenzaldehyde (CAS: 476620-54-9) typically synthesized?

Answer

2-Bromo-4,5-difluorobenzaldehyde
2-Bromo-4,5-difluorobenzaldehyde (CAS: 476620-54-9) is typically synthesized via the bromination of 4,5-difluorobenzaldehyde using bromine in the presence of a Lewis acid catalyst like aluminum bromide. The reaction proceeds through an electrophilic aromatic substitution mechanism, yielding the desired product with good selectivity and moderate to high yield depending on the reaction conditions and catalyst choice.

About

English Name 2-Bromo-4,5-difluorobenzaldehyde
Molecular Formula C7H3BrF2O
Molecular Weight 220.99999999999997 g/mol
SMILES C1=C(C(=CC(=C1F)F)Br)C=O
InChIKey ZHSZEWFWVDLMDL-UHFFFAOYSA-N
Last Updated: 2025-10-08 00:58

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