Compound Q&A
How is 3,5-Bis(2-methyl-2-propanyl)benzoic acid (CAS: 16225-26-6) typically synthesized?
Answer
3,5-Bis(2-methyl-2-propanyl)benzoic acid is typically synthesized via the Friedel-Crafts alkylation of benzoic acid with 2-methyl-2-propanol. The reaction is catalyzed by aluminum chloride, and under these conditions, the stereochemistry at the 3 and 5 positions of the aromatic ring is controlled to yield the desired product with high selectivity.
About
CAS No
16225-26-6
English Name
3,5-Bis(2-methyl-2-propanyl)benzoic acid
Molecular Formula
C15H22O2
Molecular Weight
234.34 g/mol
SMILES
CC(C)(C)C1=CC(=CC(=C1)C(=O)O)C(C)(C)C
InChIKey
NCTSLPBQVXUAHR-UHFFFAOYSA-N
Last Updated: 2025-10-08 00:58
