Compound Q&A
How is Cobamamide (CAS: 13870-90-1) typically synthesized?
Answer
Cobamamide is typically synthesized from vitamin B12, also known as cobalamin, by reacting it with an amine in the presence of a suitable solvent. The yield is generally around 80-90%, with high selectivity for the desired cobamamide product.
About
CAS No
13870-90-1
English Name
Cobamamide
Molecular Formula
C72H100CoN18O17P
Molecular Weight
1579.6 g/mol
SMILES
CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=N7)C=C8C(C(C(=N8)C(=C4[N-]5)C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[CH2-]C1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O.[Co+3]
InChIKey
OAJLVMGLJZXSGX-SLAFOUTOSA-L
Last Updated: 2025-10-08 00:58
