Compound Q&A

How is 2-Methyl-1,2-di(3-pyridinyl)-1-propanone (CAS: 54-36-4) typically synthesized?

Answer

2-Methyl-1,2-di(3-pyridinyl)-1-propanone
2-Methyl-1,2-di(3-pyridinyl)-1-propanone (CAS: 54-36-4) is typically synthesized via a condensation reaction between 3-pyridylmethyl ketone and 3-pyridylmethyl aldehyde, catalyzed by a Lewis acid such as zinc chloride. The yield is generally between 70-80%, and the reaction is conducted under mild conditions to ensure good selectivity.

About

CAS No 54-36-4
English Name 2-Methyl-1,2-di(3-pyridinyl)-1-propanone
Molecular Formula C14H14N2O
Molecular Weight 226.28 g/mol
SMILES CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
InChIKey FJLBFSROUSIWMA-UHFFFAOYSA-N
Last Updated: 2025-10-08 00:58

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