2-Methyl-1,2-di(3-pyridinyl)-1-propanone(CAS: 54-36-4)

2-Methyl-1,2-di(3-pyridinyl)-1-propanone (CAS: 54-36-4) is a crystalline solid with a molecular weight of approximately 238.2 g/mol. It is poorly soluble in water but soluble in organic solvents like acetone and ethanol. The compound is moderately reactive, particularly towards nucleophiles. It does not exhibit significant basicity or acidity under normal conditions.

2-Methyl-1,2-di(3-pyridinyl)-1-propanone (CAS: 54-36-4) is typically synthesized via a condensation reaction between 3-pyridylmethyl ketone and 3-pyridylmethyl aldehyde, catalyzed by a Lewis acid such as zinc chloride. The yield is generally between 70-80%, and the reaction is conducted under mild conditions to ensure good selectivity.

2-Methyl-1,2-di(3-pyridinyl)-1-propanone (CAS: 54-36-4) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring pyridine-based functional groups. It is also utilized in the polymer industry for the development of advanced materials, and in the sensor industry for its reactivity towards specific chemical species.

When handling 2-Methyl-1,2-di(3-pyridinyl)-1-propanone (CAS: 54-36-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. In the event of a spill, it should be cleaned up carefully according to the SDS (Safety Data Sheet) guidelines. Always refer to the SDS for detailed safety information.