Compound Q&A
How is Disodium 2'-deoxy-5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]uridine (CAS: 102814-08-4) typically synthesized?
Answer
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Disodium 2'-deoxy-5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]uridine is synthesized through a multistep process involving the protection of the nucleoside, installation of the phosphorus-containing group, and subsequent deprotection. Commonly used catalysts include organotin compounds, and the synthesis typically yields 60-70% purity with high selectivity towards the desired product.
About
CAS No
102814-08-4
English Name
Disodium 2'-deoxy-5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]uridine
Molecular Formula
C9H13N2Na2O14P3
Molecular Weight
468.14 g/mol
SMILES
C1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
InChIKey
MYSPQSAAHPZTGA-CDNBRZBRSA-L
Last Updated: 2025-10-08 00:58
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