Compound Q&A

How is 2-[(3-Chloro-2-methylphenyl)amino]nicotinic acid - L-lysine (1:1) (CAS: 55837-30-4) typically synthesized?

Answer

2-[(3-Chloro-2-methylphenyl)amino]nicotinic acid - L-lysine (1:1)
2-[(3-Chloro-2-methylphenyl)amino]nicotinic acid - L-lysine (1:1) is synthesized through a multi-step process involving coupling of nicotinoyl chloride with 3-chloro-2-methylphenylamine followed by the addition of L-lysine. The reaction is catalyzed by a base, with high selectivity and yield, typically around 95%.

About

CAS No 55837-30-4
English Name 2-[(3-Chloro-2-methylphenyl)amino]nicotinic acid - L-lysine (1:1)
Molecular Formula C19H25ClN4O4
Molecular Weight 408.89 g/mol
SMILES CC1=C(C=CC=C1Cl)NC2=C(C=CC=N2)C(=O)O.C(CCN)CC(C(=O)O)N
InChIKey CVNFYQCHAWFYQI-ZSCHJXSPSA-N
Last Updated: 2025-10-07 19:42

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