Compound Q&A

Are there alternatives to Apremilast Impurity 66 (CAS: 16533-45-2) in synthesis?

Answer

Apremilast Impurity 66
In the synthesis of drugs containing Apremilast Impurity 66 (CAS: 16533-45-2), chemists often explore alternative reagents such as other impurities or isomers that can serve as viable substitutes. These alternatives can offer similar reactivity but with different impurity profiles, providing flexibility in synthetic routes.

About

CAS No 16533-45-2
English Name Apremilast Impurity 66
Molecular Formula C10H9NO6
Molecular Weight 239.18 g/mol
SMILES CCOC(=O)C1=C(C(=CC=C1)[N+](=O)[O-])C(=O)O
InChIKey SZAOZGFHEAVFMM-UHFFFAOYSA-N
Last Updated: 2025-10-05 19:44

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