Compound Q&A

How is 3,6-Dichloro-4-methylpyridazine (CAS: 19064-64-3) typically synthesized?

Answer

3,6-Dichloro-4-methylpyridazine
3,6-Dichloro-4-methylpyridazine can be synthesized via the reaction of 4-methylpyridine with chlorine in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is selective and provides good yield under mild conditions. The process involves electrophilic aromatic substitution and results in the introduction of chloro substituents at the 3 and 6 positions.

About

CAS No 19064-64-3
English Name 3,6-Dichloro-4-methylpyridazine
Molecular Formula C5H4Cl2N2
Molecular Weight 163.01 g/mol
SMILES CC1=CC(=NN=C1Cl)Cl
InChIKey ROYHWGZNGMXQEU-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54

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