Compound Q&A

How is 4-Bromo-N-phenylaniline (CAS: 54446-36-5) typically synthesized?

Answer

4-Bromo-N-phenylaniline
4-Bromo-N-phenylaniline is typically synthesized by reacting anisidine with bromine in the presence of an appropriate Lewis acid catalyst, such as aluminum bromide. The reaction provides good yield and selectivity, with the key step involving electrophilic aromatic substitution. The product can then be purified by recrystallization or other chromatographic techniques.

About

CAS No 54446-36-5
English Name 4-Bromo-N-phenylaniline
Molecular Formula C12H10BrN
Molecular Weight 248.12 g/mol
SMILES C1=CC=C(C=C1)NC2=CC=C(C=C2)Br
InChIKey CCIVUDMVXNBUCY-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54

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