What regulatory guidelines apply to 1-Methyl-3-phenylpiperazine (CAS: 5271-27-2)?

1-Methyl-3-phenylpiperazine (CAS: 5271-27-2) is subject to various regulatory guidelines. Globally Harmonized System (GHS) classifications categorize it as a substance of low acute toxicity. Under REACH regulations, manufacturers and importers are required to conduct hazard assessments and register the substance if the tonnage threshold is exceeded. Additionally, the U.S. Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) regulate its use and disposal in pharmaceuticals and industrial processes. Compliance with these regulations ensures safe handling and disposal.