Compound Q&A

How is 2,4,5-Trifluorobenzonitrile (CAS: 98349-22-5) typically synthesized?

Answer

2,4,5-Trifluorobenzonitrile
2,4,5-Trifluorobenzonitrile (CAS: 98349-22-5) is commonly synthesized via the nitrilation of 2,4,5-trifluorobromobenzene using aqueous ammonia in the presence of a phase transfer catalyst. This method provides high yields and good selectivity, with the reaction typically requiring mild conditions to avoid over-nitrilation.

About

CAS No 98349-22-5
English Name 2,4,5-Trifluorobenzonitrile
Molecular Formula C7H2F3N
Molecular Weight 157.09 g/mol
SMILES C1=C(C(=CC(=C1F)F)F)C#N
InChIKey DLKNOGQOOZFICZ-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42

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