2,4,5-Trifluorobenzonitrile(CAS: 98349-22-5)

2,4,5-Trifluorobenzonitrile (CAS: 98349-22-5) is a colorless or light yellow liquid with a molecular weight of approximately 166.07 g/mol. It has a high boiling point and low solubility in water. This compound is known for its strong reactivity in nucleophilic substitution reactions and is less reactive towards electrophilic aromatic substitution due to the electron-withdrawing nature of the fluorine substituents.

2,4,5-Trifluorobenzonitrile (CAS: 98349-22-5) is commonly synthesized via the nitrilation of 2,4,5-trifluorobromobenzene using aqueous ammonia in the presence of a phase transfer catalyst. This method provides high yields and good selectivity, with the reaction typically requiring mild conditions to avoid over-nitrilation.

2,4,5-Trifluorobenzonitrile (CAS: 98349-22-5) finds applications in the pharmaceutical industry for the synthesis of intermediate compounds, in the polymer industry for the production of advanced materials, and in the semiconductor industry for the fabrication of electronic devices. It is also used in the development of sensors and as a precursor in other chemical processes.

When handling 2,4,5-Trifluorobenzonitrile (CAS: 98349-22-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of fumes. Spills should be cleaned up immediately, and the material should be stored in a cool, dry place away from incompatible materials. Refer to the Safety Data Sheet (SDS) for detailed information and emergency response procedures.