Compound Q&A

How is 3-Bromo-2-thiophenecarboxylic acid (CAS: 7311-64-0) typically synthesized?

Answer

3-Bromo-2-thiophenecarboxylic acid
3-Bromo-2-thiophenecarboxylic acid is typically synthesized by bromination of 2-thiophenecarboxylic acid. The bromination is usually carried out using bromine in the presence of a Lewis acid catalyst, such as aluminum bromide, in an appropriate solvent like dichloromethane. The reaction is exothermic and should be performed under nitrogen atmosphere to avoid side reactions.

About

CAS No 7311-64-0
English Name 3-Bromo-2-thiophenecarboxylic acid
Molecular Formula C5H3BrO2S
Molecular Weight 207.04799999999997 g/mol
SMILES C1=CSC(=C1Br)C(=O)O
InChIKey VQQLWBUTTMNMFT-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42

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