Compound Q&A
How is 1-[4-(Trifluoromethyl)phenyl]-1-propanone (CAS: 711-33-1) typically synthesized?
Answer
![1-[4-(Trifluoromethyl)phenyl]-1-propanone](https://static.chemtradehub.com/structs/711/711-33-1-b511.webp "1-[4-(Trifluoromethyl)phenyl]-1-propanone")
1-[4-(Trifluoromethyl)phenyl]-1-propanone (CAS: 711-33-1) can be synthesized via a Friedel-Crafts acylation reaction. This involves the reaction of 4-(trifluoromethyl)benzoyl chloride with acetone in the presence of aluminum chloride as a Lewis acid catalyst. The reaction typically provides high yields and good selectivity, making it a suitable method for industrial-scale production.
About
CAS No
711-33-1
English Name
1-[4-(Trifluoromethyl)phenyl]-1-propanone
Molecular Formula
C10H9F3O
Molecular Weight
202.17499999999995 g/mol
SMILES
CCC(=O)C1=CC=C(C=C1)C(F)(F)F
InChIKey
QFKOWENRSZZLPK-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42
![查看Leyan Reagents的1-[4-(Trifluoromethyl)phenyl]-1-propanone](https://static.chemtradehub.com/suppliers/67ce1f8657537e5c8069b370/67ce1f8657537e5c8069b370-logo.webp){kind=logo}
![查看ShangHaiChuangSai Technology Co Ltd的1-[4-(Trifluoromethyl)phenyl]-1-propanone](https://static.chemtradehub.com/suppliers/67cecce82b2de6e8e95a5e02/67cecce82b2de6e8e95a5e02-logo.webp){kind=logo}
![查看ShangHaiJiZhiShengHua Technology Co Ltd的1-[4-(Trifluoromethyl)phenyl]-1-propanone](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp){kind=logo}
![查看HuBeiMoDe Chemical Co Ltd的1-[4-(Trifluoromethyl)phenyl]-1-propanone](https://static.chemtradehub.com/suppliers/67cecc352b2de6e8e95a5c3a/67cecc352b2de6e8e95a5c3a-logo.webp){kind=logo}