Compound Q&A
How is Imidapril Hydrochloride (CAS: 89396-94-1) typically synthesized?
Answer
Imidapril Hydrochloride is synthesized by the condensation of 2-chloro-6-ethyl-1,4-benzenediamine with 2-aminobenzonitrile followed by hydrolysis and hydrochloride formation. The reaction is catalyzed by Lewis acids such as aluminum chloride and proceeds with good selectivity and yield, making it a feasible industrial synthesis route.
About
CAS No
89396-94-1
English Name
Imidapril Hydrochloride
Molecular Formula
C20H28ClN3O6
Molecular Weight
441.91 g/mol
SMILES
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C2=O)C)C(=O)O.Cl
InChIKey
LSLQGMMMRMDXHN-GEUPQXMHSA-N
Last Updated: 2025-10-01 21:42
