Compound Q&A
How is 3,3-Difluoropyrrolidine hydrochloride (CAS: 163457-23-6) typically synthesized?
Answer
3,3-Difluoropyrrolidine hydrochloride can be synthesized via the reaction of 3,3-difluoro-1,2-dihydro-2-oxopyrrole with hydrochloric acid. This process involves the formation of the salt, followed by recrystallization to obtain the desired product. The reaction is typically carried out in aqueous conditions, and the yield is around 70-80%. Catalysts and other reagents may be used to improve selectivity and yield.
About
CAS No
163457-23-6
English Name
3,3-Difluoropyrrolidine hydrochloride (1:1)
Molecular Formula
C4H8ClF2N
Molecular Weight
143.56 g/mol
SMILES
Cl.FC1(F)CCNC1
InChIKey
YYVPZQADFREIFR-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42
