Compound Q&A
How is 3-Fluoroisonicotinic acid (CAS: 393-53-3) typically synthesized?
Answer
3-Fluoroisonicotinic acid (CAS: 393-53-3) can be synthesized by fluorinating isonicotinic acid using a phase transfer catalyst such as tetrabutylammonium fluoride in an aprotic solvent. The reaction typically proceeds with a yield of 80-85%. Other methods involve direct fluorination of nicotinic acid derivatives.
About
CAS No
393-53-3
English Name
3-Fluoroisonicotinic acid
Molecular Formula
C6H4FNO2
Molecular Weight
141.1 g/mol
SMILES
C1=CN=CC(=C1C(=O)O)F
InChIKey
POLXLLIQWDBJMD-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
