Compound Q&A

How is 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate (CAS: 16432-81-8) typically synthesized?

Answer

2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate
2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate (CAS: 16432-81-8) is synthesized through the condensation of acryloyl chloride with 4-benzoyl-3-hydroxyphenol. This reaction is catalyzed by a Lewis acid such as aluminum trichloride and typically proceeds with good yield. The compound can also be prepared by the acrylation of 4-benzoyl-3-hydroxyphenol with acrylic anhydride in the presence of a base like pyridine.

About

CAS No 16432-81-8
English Name 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate
Molecular Formula C18H16O5
Molecular Weight 312.32 g/mol
SMILES C=CC(=O)OCCOC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O
InChIKey NMMXJQKTXREVGN-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51

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