Compound Q&A
How is 4-[3-(Trifluoromethyl)-3H-diaziren-3-yl]benzoic acid (CAS: 85559-46-2) typically synthesized?
Answer
![4-[3-(Trifluoromethyl)-3H-diaziren-3-yl]benzoic acid](https://static.chemtradehub.com/structs/855/85559-46-2-cf86.webp "4-[3-(Trifluoromethyl)-3H-diaziren-3-yl]benzoic acid")
4-[3-(Trifluoromethyl)-3H-diaziren-3-yl]benzoic acid is typically synthesized through a diazo coupling reaction involving trifluoromethyl azide and benzoic acid. The reaction is typically catalyzed by a Lewis acid like aluminum trichloride or titanium(IV) isopropoxide. The yield can be optimized by controlling the reaction temperature and time.
About
CAS No
85559-46-2
English Name
4-[3-(Trifluoromethyl)-3H-diaziren-3-yl]benzoic acid
Molecular Formula
C9H5F3N2O2
Molecular Weight
230.14 g/mol
SMILES
c1cc(ccc1C(=O)O)C2(N=N2)C(F)(F)F
InChIKey
CZPAJVBVULSLGG-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
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