Compound Q&A

How is N-[(4-Methylphenyl)sulfonyl]glycine (CAS: 1080-44-0) typically synthesized?

Answer

N-[(4-Methylphenyl)sulfonyl]glycine
N-[(4-Methylphenyl)sulfonyl]glycine is typically synthesized by the reaction of 4-methylphenyl sulfonyl chloride with glycine. The reaction involves the substitution of the amino group of glycine by the sulfonyl group from 4-methylphenyl sulfonyl chloride. The yield is generally high, and the use of a suitable catalyst can enhance the reaction selectivity.

About

CAS No 1080-44-0
English Name N-[(4-Methylphenyl)sulfonyl]glycine
Molecular Formula C9H11NO4S
Molecular Weight 229.26 g/mol
SMILES CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)O
InChIKey VDKFCCZUCXYILI-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51

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