N-[(4-Methylphenyl)sulfonyl]glycine(CAS: 1080-44-0)

N-[(4-Methylphenyl)sulfonyl]glycine (CAS: 1080-44-0) is a crystalline solid with a molecular weight of approximately 275.25 g/mol. Its solubility in water is low, around 0.1 g/L. It is reactive due to the sulfonyl group, which can participate in various chemical reactions. It is stable under normal conditions but should be stored away from direct sunlight and heat.

N-[(4-Methylphenyl)sulfonyl]glycine is typically synthesized by the reaction of 4-methylphenyl sulfonyl chloride with glycine. The reaction involves the substitution of the amino group of glycine by the sulfonyl group from 4-methylphenyl sulfonyl chloride. The yield is generally high, and the use of a suitable catalyst can enhance the reaction selectivity.

N-[(4-Methylphenyl)sulfonyl]glycine (CAS: 1080-44-0) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer, and in the semiconductor industry for the fabrication of electronic materials. Additionally, it is used in the development of sensors and other advanced materials.

When handling N-[(4-Methylphenyl)sulfonyl]glycine (CAS: 1080-44-0), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Ensure that the work is conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate materials, and the substance should be stored in a cool, dry place away from direct sunlight. Always consult the Safety Data Sheet (SDS) for detailed safety information.