Compound Q&A
How is 2-Chloro-1-(3-chlorophenyl)ethanone (CAS: 21886-56-6) typically synthesized?
Answer
2-Chloro-1-(3-chlorophenyl)ethanone (CAS: 21886-56-6) can be synthesized via the acylation of 3-chlorophenylmethanol with chloroacetyl chloride. The reaction is catalyzed by a Lewis acid such as aluminum chloride. The yield is typically around 70-80%. The process requires careful monitoring of temperature and pH to ensure high selectivity and yield.
About
CAS No
21886-56-6
English Name
2-Chloro-1-(3-chlorophenyl)ethanone
Molecular Formula
C8H6Cl2O
Molecular Weight
189.04 g/mol
SMILES
C1=CC(=CC(=C1)Cl)C(=O)CCl
InChIKey
AVUVSYIYUADCKE-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
