Compound Q&A

Are there alternatives to 2,2,2-Trifluoroethyl 4-methylbenzenesulfonate (CAS: 433-06-7) in synthesis?

Answer

2,2,2-Trifluoroethyl 4-methylbenzenesulfonate
While 2,2,2-Trifluoroethyl 4-methylbenzenesulfonate (CAS: 433-06-7) is a useful reagent in organic synthesis, there are alternative compounds such as trifluoroethyl 4-chlorobenzenesulfonate and trifluoroethyl benzenesulfonate. These alternatives may offer similar functionalities but with different reactivity and stability, making them suitable for different synthetic routes.

About

CAS No 433-06-7
English Name 2,2,2-Trifluoroethyl 4-methylbenzenesulfonate
Molecular Formula C9H9F3O3S
Molecular Weight 254.23 g/mol
SMILES CC1=CC=C(C=C1)S(=O)(=O)OCC(F)(F)F
InChIKey IGKCQDUYZULGBM-UHFFFAOYSA-N
Last Updated: 2025-09-30 00:13

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