Compound Q&A
How is 5-Chloronicotinic acid (CAS: 22620-27-5) typically synthesized?
Answer
5-Chloronicotinic acid (CAS: 22620-27-5) is typically synthesized by chlorination of nicotinic acid with thionyl chloride. The reaction is carried out in the presence of a solvent like dichloromethane, and a high yield is achieved. The reaction is selective and produces a pure product with good yield.
About
CAS No
22620-27-5
English Name
5-Chloronicotinic acid
Molecular Formula
C6H4ClNO2
Molecular Weight
157.56 g/mol
SMILES
C1=C(C=NC=C1Cl)C(=O)O
InChIKey
XYLPLVUYPAPCML-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43
