Compound Q&A
How is 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine (CAS: 71701-92-3) typically synthesized?
Answer
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine is typically synthesized by bromination of 2-chloro-5-(trifluoromethyl)pyridine using N-bromosuccinimide (NBS) as the brominating agent. The reaction is carried out in an inert solvent like dichloromethane. The yield can be enhanced by using a radical initiator and controlling the reaction temperature and time to achieve high selectivity.
About
CAS No
71701-92-3
English Name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Molecular Formula
C6H2BrClF3N
Molecular Weight
260.44 g/mol
SMILES
C1=C(C=NC(=C1Br)Cl)C(F)(F)F
InChIKey
GVQLMGPWTHAUPV-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43
