Compound Q&A

How is tert-butyl N-(azetidin-3-ylmethyl)carbamate (CAS: 91188-15-7) typically synthesized?

Answer

tert-butyl N-(azetidin-3-ylmethyl)carbamate
Tert-butyl N-(azetidin-3-ylmethyl)carbamate is typically synthesized via the reaction of tert-butyl isocyanate with azetidin-3-carboxylic acid. The reaction is conducted in the presence of a suitable solvent like dichloromethane. The yield is usually good, and the product is isolated by column chromatography. This reaction requires careful handling due to the reactivity of isocyanates.

About

CAS No 91188-15-7
English Name tert-butyl N-(azetidin-3-ylmethyl)carbamate
Molecular Formula C9H18N2O2
Molecular Weight 186.25 g/mol
SMILES CC(C)(C)OC(=O)NCC1CNC1
InChIKey MOLUHRBHXXGWDP-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06

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