Compound Q&A
How is (2S)-4-Methoxy-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-4-oxobutanoic acid (CAS: 59768-74-0) typically synthesized?
Answer
![(2S)-4-Methoxy-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-4-oxobutanoic acid](https://static.chemtradehub.com/structs/597/59768-74-0-a3f5.webp "(2S)-4-Methoxy-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-4-oxobutanoic acid")
(2S)-4-Methoxy-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-4-oxobutanoic acid is synthesized via the condensation of 2-methyl-2-propanol with 4-methoxy-4-oxobutanoic acid, followed by amidation using a suitable amine. Commonly, this reaction is catalyzed by a strong acid such as trifluoroacetic acid, with a yield of around 70-80%. The reaction is conducted in a solvent like dichloromethane or ethanol.
About
CAS No
59768-74-0
English Name
(2S)-4-Methoxy-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-4-oxobutanoic acid
Molecular Formula
C10H17NO6
Molecular Weight
247.25 g/mol
SMILES
CC(C)(C)OC(=O)NC(CC(=O)OC)C(=O)O
InChIKey
WFPSMPYVXFVVFA-LURJTMIESA-N
Last Updated: 2025-09-28 13:06
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