Compound Q&A
How is (4S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide (CAS: 154127-42-1) typically synthesized?
Answer
![(4S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide](https://static.chemtradehub.com/structs/154/154127-42-1-9a18.webp "(4S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide")
(4S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide is synthesized through a multi-step process involving the reaction of 3-methoxypropyl chloride with 4-hydroxy-2-(thieno[3,2-e][1,2]thiazin-6-sulfonamido)butyric acid in the presence of a base such as triethylamine. The reaction is carried out in an organic solvent like dichloromethane. The yield is around 75%, and the product is purified by recrystallization.
About
CAS No
154127-42-1
English Name
(4S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
Molecular Formula
C10H16N2O6S3
Molecular Weight
356.45 g/mol
SMILES
COCCCN1CC(C2=C(S1(=O)=O)SC(=C2)S(=O)(=O)N)O
InChIKey
UHIWBQIWXWWDKT-MRVPVSSYSA-N
Last Updated: 2025-09-28 13:06