Compound Q&A

How is Ethenzamide (CAS: 938-73-8) typically synthesized?

Answer

Ethenzamide
Ethenzamide is typically synthesized through the amidation of ethyl acetoacetate with ammonia or an amine under basic conditions. The reaction is usually catalyzed by sodium hydroxide. The process yields a mixture of products, but the desired ethenzamide can be isolated by recrystallization. The reaction is selective and the yield is generally good, around 70-85%.

About

CAS No 938-73-8
English Name Ethenzamide
Molecular Formula C9H11NO2
Molecular Weight 165.19 g/mol
SMILES CCOC1=CC=CC=C1C(=O)N
InChIKey SBNKFTQSBPKMBZ-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06

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