Compound Q&A

How is Albendazole Impurity 5 (CAS: 54029-45-7) typically synthesized?

Answer

Albendazole Impurity 5 (2-Nitro-4-Thiocyanatoaniline)
Albendazole Impurity 5 (CAS: 54029-45-7) is typically synthesized through a multi-step process involving nitration and thiocyanation reactions. The process requires careful control of reaction conditions to achieve high selectivity and yield. Commonly used catalysts include sulfuric acid and sodium thiocyanate. Detailed procedures are available in the literature and industrial patents.

About

CAS No 54029-45-7
English Name Albendazole Impurity 5 (2-Nitro-4-Thiocyanatoaniline)
Molecular Formula C7H5N3O2S
Molecular Weight 17.03 g/mol
SMILES C1=CC(=C(C=C1SC#N)[N+](=O)[O-])N
InChIKey QUWHIBBGKKRYFW-UHFFFAOYSA-N
Last Updated: 2025-09-28 13:06

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