Compound Q&A

How is (1S)-2-Chloro-1-(2,4-dichlorophenyl)ethanol (CAS: 126534-31-4) typically synthesized?

Answer

(1S)\u200b-\u200b2-\u200bChloro-\u200b1-\u200b(2,\u200b4-\u200bdichlorophenyl)\u200bethanol
(1S)-2-Chloro-1-(2,4-dichlorophenyl)ethanol is usually synthesized via the coupling of 2,4-dichlorophenyl chloromethyl ether with chloroethanol in the presence of a base such as sodium hydride. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The product is then isolated and purified through crystallization or other separation techniques.

About

English Name (1S)\u200b-\u200b2-\u200bChloro-\u200b1-\u200b(2,\u200b4-\u200bdichlorophenyl)\u200bethanol
Molecular Formula C8H7Cl3O
Molecular Weight 225.4996 g/mol
SMILES ClC[C@H](c1ccc(cc1Cl)Cl)O
InChIKey XHEPANNURIQWRM-MRVPVSSYSA-N
Last Updated: 2025-09-28 13:06

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